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jove.com
Video: Laminins are the Adhesive Proteins of Basal Lamina
2.6K Views. Laminins are heterotrimeric proteins with high molecular mass found in the extracellular matrix. Each laminin molecule is composed of three chains, viz. alpha, beta, and gamma, coded by five, four, and three paralogous genes, respectively. Laminins are categories based on the compositions of the three chains. In humans, the five ...
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Laminin is an essential protein in the extracellular matrix that functions like molecular glue, allowing cells to attach to one another and to their surrounding structures. Often depicted with a cross-like shape, it forms a structural framework that helps maintain tissue integrity and organizes cells into functional layers. Laminin is crucial for organ development, repair, and long-term stability, guiding cells to their proper locations and helping tissues retain their form. Without it, cells wo
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