The US Food and Drug Administration (FDA) recently highlighted three case studies showing how sponsors can incorporate innovative study designs in their clinical trials using the agency’s Complex ...

From outbreak investigations to clinical trials, the right study design can make or break public health research. Understanding the strengths, limitations, and applications of each approach helps ...

SAN DIEGO, CA—Does the use of a primary composite endpoint help or harm when it comes to interpreting modern-day clinical trials? Do softer clinical endpoints, such as recurrent angina, restenosis, or ...

Understanding epidemiological and clinical study designs is key to producing reliable health evidence. From descriptive reports to randomized trials, each design has unique strengths and limitations.

New design frameworks also facilitate the inclusion of basket trials as subcomponents of platform trials. 20 The fusion of basket and platform trials may accommodate exploratory and confirmatory study ...

Clinical trials are well-controlled and designed experiments that aim to prove that an Investigational Medicinal Product (IMP) is effective. Clinical trial data is submitted to the national health ...

We study design in all its manifestations, with a focus on its implications. Do you care about design and its impact on the individual, society, and the environment? Are you interested in honing your ...