The contractile responses of esophageal smooth muscle (SM) induced by platelet-activating factor (PAF) involve the activation of L-type voltage-dependent calcium channels (L-type VDCCs), ...
A research group led by Dr. Keisuke Obara, Dr. Kento Yoshioka, and Professor Yoshio Tanaka from the Department of Chemical Pharmacology, Faculty of Pharmaceutical Sciences, Toho University, has ...
Ferulic acid suppresses ileal smooth muscle contraction by inhibiting calcium ion influx through voltage-dependent calcium channels. This action may help prevent or treat excessive intestinal motility ...
The treatments for bronchospam have not changed in the past 50 years, Panettieri said, since they work for most - but not all people. The microdevice allowed us to drill down into how single cells ...
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Genetic model reveals a form of calcium release is unnecessary for normal muscle contraction
Because RyR1 is also expressed in neurons, immune cells, and vascular smooth muscle, the E3896A model offers a unique tool to examine CICR's broader physiological roles. By combining gene engineering, ...
Panel A shows the microscopic myoarchitecture of the circular and longitudinal muscle layers of the lower esophageal sphincter and stomach. The circular muscle fibers of the esophagus cross each other ...
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