Researchers have found a new receptor for nerve growth factor that plays an important role in pain signaling, even though it does not signal on its own, according to a new study. The findings hold ...

Researchers at the NYU Pain Research Center have found a new receptor for nerve growth factor that plays an important role in pain signaling, even though it does not signal on its own, according to a ...

Key cancer link: Researchers found BFT must bind to the claudin-4 receptor before harming colon cells, resolving a long-standing mystery. Potential prevention path: A molecular decoy mimicking claudin ...

A team has demonstrated new mechanisms that are involved in the development of inflammatory cardiovascular diseases. A team led by LMU researchers Christian Weber and Yvonne Döring has demonstrated ...

New service offering enables GR/NF-κB transrepression studies to support deeper mechanism-of-action insight in drug ...

A single molecule that tricks its way into fat cells by mimicking a gut hormone, then releases a second drug once inside, has ...

Results From First-in-Human Phase I Study of a Novel CD19-1XX Chimeric Antigen Receptor With Calibrated Signaling in Large B-Cell Lymphoma The following represents disclosure information provided by ...

GLP-1 RA use is associated with a lower risk of developing Parkinson disease compared with sulfonylurea use in a large cohort study.

Cell signaling is crucial for cells to communicate and function correctly. Disruptions in these pathways, caused by genetic mutations or environmental factors, can lead to uncontrolled cell growth, ...

Nerve growth factor receptor TrkA (in green) and co-receptor NRP1 (in purple) are coexpressed in the same nerve cells in mice. Researchers at the NYU Pain Research Center have found a new receptor for ...