Localized scleroderma, as the term denotes, is localized to the skin on the hands and face. It is characterized by slow progression and rarely transforms to the systemic type. Localized scleroderma is ...

A 55-year-old woman with a history of scleroderma presented after 5 days of experiencing fever, chills and progressive swelling of her right thumb (Fig. 1). The thumb was exquisitely tender to touch.

The management of patients with systemic sclerosis (SSc) can be challenging because disease-associated damage is often difficult to reverse and curative therapies are not yet available. Early ...

Most people with scleroderma have autoantibodies. Several scleroderma-specific antibodies have been identified. These can help with diagnosis and give insight into the type of disease you may ...

Scleroderma, also sometimes referred to as systemic sclerosis, is a chronic autoimmune disorder that involves a progressive hardening of the skin. An excess of collagen and other connective tissues in ...

Scleroderma survivor, Susan Spence-Le Gendre has been battling the life-threatening condition for over a decade. The discomfort never stops pain, fatigue, weakness, aching muscles, joints and bones, ...