Signs of neurodegeneration in individuals with Down syndrome may start as early as birth, a critical stage of brain ...

Rebecca and Luke Chambers keep an eye on Cal Chambers as he climbs a ladder at one of his favorite places, the playground at John Venezia Community Park on Wednesday, Nov. 5, 2025. (The Gazette, ...

Scientists in Japan have used gene-editing technology to remove the extra chromosome responsible for Down syndrome, at least in lab-grown human cells. The project, led by Dr. Ryotaro Hashizume of Mie ...

Nearly half of all babies born with Down syndrome face congenital heart defects, often involving serious malformations that require surgery in the first months of life. For decades, scientists have ...

The ethics of using safe gene therapies to improve the health and cognition of Down syndrome children and adults.

A cellular-resolution map of prenatal brain development in Down syndrome reveals disrupted neuron production timing and altered cell types.

Cutting-edge technology could one day transform treatment for Down syndrome, as researchers have successfully deleted an extra chromosome in lab-grown cells. Down syndrome - which occurs when a person ...